• Getting Started

   

     

  Getting started with PathoGenius^®

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• Wound Care

   

     

  PathoGenius^® offers DNA guided, personalized medicine for wound care.

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• ENT and Respiratory Tract

   

   

  PathoGenius^® offers specifically designed Rapid screening for ENT applications and comprehensive bacterial and fungal diagnostics.

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• Respiratory Viral Panel

   

   

  PathoGenius^® extends rapid screen molecular diagnostics for ENT and respiratory viruses.

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• Bacterial Vaginosis/Yeast Infections

   

   

  PathoGenius^® offers specifically designed Rapid screening for BV as well as comprehensive bacterial and fungal diagnostics persistent infections.

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Services:

Accredited, Reliable, and Fast Molecular Diagnostics Tailored for Your Practice Needs

 

Testing Options

Two types of molecular microbial diagnostic tests are offered at PathoGenius^®. In both types of analysis, the microbial DNA is extracted from the patient's swab, washing, or tissue sample. The microbial DNA is then analyzed using molecular diagnostic methods. The report contains information about the pathogenic organisms detected.

 

The Level 1 Rapid Screen diagnostic panels are designed for each specific application to screen for about 24 of the most commonly identified microbes of concern in that field of medicine using quantitative PCR. Thus, the Level 1 Wound panel is different from the Level 1 ENT panel.

 

The Level 2 DecodEX^TM test sequences the entire microbial DNA from the sample and identifies the pathogens and the relative percent abundance in which they appear in the sample. More information is available below.

 

The Respiratory Viral Panel offered by PathoGenius^® is the most sensitive rapid screen test available for targeted respiratory viruses based on an independent study. Utilizing both bacterial and viral molecular diagnostic panels guides physicians in selecting the most targeted effective approach for community-acquired pneumonia and other respiratory infections.

 

 

Getting Started with PathoGenius^®:

Sample collection and shipping kits supplied by PathoGenius^® instill quality assurance in diagnostic results by following proper specimen management according to the American Society for Microbiology Guidelines in the following ways:

 

1.  Ensures that patient specimens are collected, transported, and stored properly

2.  Ensuring that the specimens arrive at the laboratory for analysis as quickly as possible

3.  Minimizes staff training by simplifying and standardizing collection materials

4.  Eliminates the need for clinic to stock perishable sampling supplies

 

The health care practitioner needs to decide what level of testing is necessary, and Contact us to obtain sample collection and shipping supplies. Collect and ship patient samples with the PathoGenius^® sample collection kits, and ship it using the pre-paid FedEx Priority Overnight shipping labels we supply. Results are delivered within 24-48 hours for Level 1 tests, and within about 1 week for Level 2 tests.

 

 

Level 1:

Rapid Screening

1.  Turn round time of approximately 24 hours from receipt of sample.

2.  The Specimen is examined for about 24 of the most commonly identified microbes of interest within the field of medicine serviced.

3.  Approximately 80% of Level 1 samples are positive for at least one pathogen.

What is Examined

For wounds and nasal screening, this rapid, quantitative screen includes:

•  Staphylococcus (including MRSA)

•  Streptococcus

•  Haemophilus

•  Enterococcus (including VRE)

•  Pseudomonas

•  Serratia

•  Candida

•  And many more...

Level 2:

DecodEX^TM Microbial Genetic Identification

1.  The microbial DNA is extracted from the specimen, and then sequenced using the most advanced next generation sequencing platforms available to specifically identify the pathogens.

2.  This method meticulously examines the sample for known/unknown pathogens.

3.  A detailed, statistical report of all pathogens is provided to you within 1 week after your samples are received.

What is Examined

Level 2 Decodex^TM test is the first universally comprehensive bacterial and fungal diagnostic test. This test determines with sequence level accuracy what the pathogens are present and in what relative abundance they appear in the sample. This process is accomplished using comparative DNA sequencing analysis, which is widely considered to be the best genotypic method for microbial identification. The most common approach is PCR amplification and sequencing of the ribosomal RNA gene. The process was originally developed around the Roche 454 pyrosequencing system. Now, data is generated by the latest, cutting edge sequencing platforms available; such as, Ion Torrent PGM, Ion Proton, and Illumina. Data is compared against a sequence database, which is constantly curated and contains only validated microbial sequences. Knowing what the pathogens are is the first step to developing a targeted therapy. Most infections are polymicrobial. PathoGenius^® diagnostics will help the physician determine what the major populations of pathogens are contributing to the bioburden of the patient, and ultimately to the disease state of the patient.

Respiratory Viral:

Rapid Screening

1. Turn around time of approximately 48 hours from the receipt of sample.

2. The specimen is examined for about 15 of the most commonly identified viruses of interest in respiratory disease.

3. A detailed report relating the presence or absence of viral components is provided

What is Examined

•   Adenovirus B/E

•   Adenovirus C

•   Human Metapneumovirus (HMPV)

•   Human Rhinovirus (HRV)

•   Influenza A

•   Influenza A 2009 H1N1

•   Influenza A H1

•   Influenza A H3

•   Influenza B

•   Parainfluenza Virus (PIV) 1

•   Parainfluenza Virus (PIV) 2

•   Parainfluenza Virus (PIV) 3

•   Respiratory Synclytial Virus (RSV) A

•   Respiratory Synclytial Virus (RSV) B